Its former principal, Rev. Sr. Damian Lai, has retired in 2006. Her job was replaced by the vice-principal, Miss Deborah Wu.
St. Paul's Secondary School was founded in 1960 by the Sisters of St. Paul of Chartres as an extension of St. Paul's Convent School to meet the growing needs of science education of girls in Hong Kong.
It has been the forerunner of science education for girls in Hong Kong. It was one of the first girls' schools in Hong Kong to offer science and computer related subjects.
It offered Integrated Science in the late 60s, Computer Studies in the late 70s, Computer Literacy and Family Life Education in the early 80s and implemented IT in Education in the 90s. It was selected as one of the 10 pilot secondary schools in the IT in Education Pilot Scheme in 1998.
There are five classes in each of Form 1 to Form 5, and three classes in each of Form 6 and Form 7, constituting a total of 31 classes. Among the 10 classes in Form 4 and 5, 6 of them are arts classes and 4 of them are science classes. Half of the Form 1 students come from St. Paul's Primary Catholic School and the rest come from other primary schools. All Form 4 and Form 6 places are filled by its own qualified students.
A number of graduates continued their education at prestigious local and overseas universities, including the University of Hong Kong, Chinese University of Hong Kong, Oxford, Cambridge, London, Princeton, University of Pennsylvania, Harvard and Massachusetts Institute of Technology.
Other sister schools:
*St. Paul's Convent School
*St. Paul's School